Topsy

A new drug combination for severe treatment-resistant depression

Depression in bipolar illness is often difficult to treat and life-threating. Frequently it fails to respond to standard treatments. In the current issue of Psychotherapy and Psychosomatics a new drug combination is suggested.A case of treatment-resistant bipolar depression with a robust remission after treatment with the combination of buspirone 5 mg and melatonin 3 mg plus bupropion... Read moreDepression in bipolar illness is often difficult to treat and life-threating. Frequently it fails to respond to standard treatments. In the current issue of Psychotherapy and Psychosomatics a new drug combination is suggested.A case of treatment-resistant bipolar depression with a robust remission after treatment with the combination of buspirone 5 mg and melatonin 3 mg plus bupropion 75 mg added to lithium and lamotrigine (with prior failure of high-dose lithium and lamotrigine alone) is reported. View page