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82 Posts by ongenetics
82 Posts by ongenetics
From in the Some of My Best Friends Are Germs #HumanMicrobiome
nyti.ms/10XrKSC
In a must-read, @michaelpollan gets microbiota science right, finding new reasons for old advice - "mostly plants."
http://t.co/6Atj4vTovC
Ptashne on histone modifications and epigenetics. "It's not just semantics."
fasebj.org/content/27/1/1.full.pdf
Ptashne says overuse of "epigenetics" "not just a matter of semantics, [but] a
question of how things actually work." http://t.co/RSd3vi4QMh
MD: de novo LoF mutations are enriched in low-IQ autism cases, but not in normal-IQ cases. Very interesting… #bog13
The discussion of pleiotropy by Fisher, Wright & others as a universal phenomenon seems relevant somehow to the debate about #ENCODE.
Nice talk by @evolvability (Mittelman) on repeatdb dot com. Repeat variability (high mutation rate) might explain missing heritability.
SCOTUS brief can be found here: Also mentions NIPT to buttress argument against broad gene patents
americanbar.org/content/dam/aba/publications/supr...s-v2/12-398_neither_amcu_lander.authcheckdam.pdf
Justices told that "Myriad's claims include DNA fragments that are unambiguously products of Nature." http://t.co/4Z9ropzgeL MT @eyeslash
As Court Considers Gene Patents, Case May Overlook Relevant Issues
nytimes.com/2013/04/15/business/as-court-consider...e-patents-case-may-overlook-relevant-issues.html
"disconnecting DNA from the chromosome changed it enough structurally to qualify for patenting" is a dumb lawyer joke http://t.co/3iZ16ka2tB
Searls: Lithe and slimy undergo a homologous double recombination event to form slithy. Ideas of evolution and linguistic influenced LC.
Searls: Remote homologs of Carroll's "Brillig" reveals relatedness to broiling, grilling and boiling. (L.C. was a bioinformatician).
Shared Horizons - Keynote Lecture
mith.umd.edu/sharedhorizons/about/keynote-lecture/
Searls: "Systems biology is post-genomic in the sense that Romanticism is post-Enlightenment" http://t.co/Or2es2OZHs
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